TABLE 3.
Lung function measurements according to bronchopulmonary dysplasia (BPD) severity
|
BPD severity |
P* | |||
|---|---|---|---|---|
| Mild | Moderate | Severe | ||
| n | 6 | 10 | 9 | – |
| Age, years, mean ± SD | 14.0±2.8 | 13.8±1.9 | 13.7±1.8 | 0.62 |
| FEV1 | 93.5±9.7 | 53.0±19.0 | 52.2±12.5 | 0.006 |
| FVC | 103.0±2.5 | 72.0±15.8 | 64.5±12.1 | 0.19 |
| FEV1/FVC | 83.8±12.8 | 68.8±23.7 | 76.3±19.0 | 0.06 |
| FEF25–75 | 83.3±17.0 | 43.2±33.6 | 34.2±18.5 | 0.001 |
| TLC | 105.7±23.8 | 113.3±35.3 | 110.5±9.2 | 0.37 |
| FRC | 104.0±71.2 | 148.0±76.9 | 163.0±24.0 | 0.07 |
| RV | 121.3±96.8 | 248.5±73.6 | 294.0±59.4 | 0.29 |
| DLCO | – | 78.0±5.0 | 55.5±6.4 | – |
Data presented as % predicted ± SD unless otherwise indicated.
*
Comparison between values across severity categories. DLCO Diffusing capacity for carbon monoxide; FEF25–75 Forced expiratory flow over the middle one-half of the forced vital capacity (FVC) manoeuvre; FEV1 Forced expiratory volume in 1 s; FRC Functional residual capacity; RV Residual volume; TLC Total lung capacity