TABLE 5.

Crude and adjusted ORs of clinical factors with long-term complications of prematurity

	Developmental delay diagnosed by 2 years of age		Attention-deficit hyperactivity disorder*		Neurological impairment diagnosed by 2 years of age
	OR (95% CI)		OR (95% CI)		OR (95% CI)
	Crude	Adjusted†	Crude	Adjusted†‡	Crude	Adjusted†
Birth weight	1.01/100 g (1.01–1.02)	1.01/100 g (1.01–1.02)	N/S		N/S	–
Gestational age	1.09/week (0.97–1.19)	–	1.45/week (1.15–1.79)	1.25/week (1.06–1.82)	1.11/week (0.98–1.26)	–
Days on mechanical ventilation	1.02/day (1.01–1.03)	1.01/day (1.00–1.03)			–	–
Initial length of hospital stay	1.01/day (1.00–1.01)	1.01/day (1.00–1.01)	N/S	–	N/S	–
Anoxic encephalopathy	N/S	–	N/S	–	5.4 (1.4–21.3)	N/S
Seizures	N/S	–	N/S	–	6.9 (2.9–15.9)	7.2 (2.9–17.6)
Postnatal corticosteroids	N/S	–	8.12 (2.4–27.6)	5.3 (1.3–22.4)	N/S	–
Prenatal betamethasone	N/S	–	N/S	–	N/S	–
Numbers of readmission	1.2 (1.1–1.3)	1.1 (1.1–1.2)	N/S	–	N/S	–
Bronchopulmonary dysplasia severity	1.9 (1.2–3.0)	N/S	N/S	–	N/S	–

^*As assessed at most recent follow-up;

^†OR adjusted for the variables listed in the first column, when found to be significant in a univariate analysis as well as for the degree of prematurity using gestational age (not in the case of developmental delay because collinearity was found between gestational age and birth weight);

^‡Also adjusted for low vision, hearing impairment and the duration of follow-up for each subject. N/S Not significant