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. 2011 Dec 16;11:59. doi: 10.1186/1471-2466-11-59

Table 3.

Inhaled Corticosteroids (ICS) and the Risk of Herpes Zoster Among Cases and Controls Treated with Inhibitors of Cytochrome Oxidase P450 3A4*

Cases (n = 475) Controls (n = 760) Crude Odds Ratio Adjusted Odds Ratio† (95% CI ‡)
ICS
no use% 35.6 36.1 1.0 reference
high dose% 24.4 20.8 1.13 1.24 (0.81-1.90)
medium dose% 16.8 18.2 0.95 0.94 (0.63-1.41)
low dose% 2.5 3.3 0.75 0.66 (0.29-1.48)

*see list of inhibitors of cytochrome P450 3A4 in methods.

†Adjusted for gender, smoking status, all the variables in Table 1, as well as past use of ICS.

‡CI: confidence interval