Table 1. Clustering results obtained from flexible docking of withanone into TPX2-Aurora A complex.
Receptor | No. of AutoDock clustersa , b | Cluster rankb | No. of structures in the cluster | Lowest binding energy of cluster | Energy range within cluster |
1 | 3 | −16.27 | −16.27 to −14.95 | ||
TPX2-Aurora A complex | 4 (10) | 2 | 2 | −15.65 | −15.65 to −14.58 |
3 | 4 | −15.61 | −15.61 to −14.35 | ||
4 | 1 | −14.63 | −14.63 to −14.63 |
Number of GA runs are shown in parentheses.
Clustering is done with RMS tolerance of 5.0 Å.