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. 2012 Jan 27;7(1):e31094. doi: 10.1371/journal.pone.0031094

Figure 4. Percentages of hippocampal granule cell expressing Arc protein 30 min after the last probe trail of the Morris water maze.

Figure 4

Two-way ANOVA revealed a significant interaction between drug treatment (DFMO vs vehicle) and injury (trauma, radiation, RCI). Animals treated with vehicle after trauma or RCI showed a significant reduction in the percentage of neurons expressing Arc relative to sham treated animals (#p<0.009, * p<0.02). There was no difference in the percentage of neurons expressing Arc between the different injury groups in the DFMO treated animals. Each treatment group consisted of 8–11 mice. Each bar represents a mean value and error bars are SEM.