Table 1.
Clinical characteristics of Finnish pre-eclampsia (PE) patients and control subjects (mean and standard deviation SD) combined from Finnish population based Data set (Data set 1), Southern Finland PE Data set (Data set 2) and Eastern Finland PE Data Set (Data set 3)
| Pre-eclampsia | Controls | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primiparous (n = 321) | Multiparous (n = 164) | Primiparous (n = 264) | Multiparous (n = 185) | Primiparous | Multiparous | |||||||||
| N | Mean | SD | N | Mean | SD | N | Mean | SD | N | Mean | SD | p* | p* | |
| Age (years) | 321 | 27.7 | 5.4 | 164 | 31.8 | 5.2 | 264 | 27.6 | 4.7 | 185 | 31.0 | 4.9 | 0.374 | 0.177 |
| BMI (kg/m2) | 302 | 23.8 | 4.5 | 162 | 24.6 | 4.4 | 264 | 22.2 | 3.1 | 185 | 23.2 | 3.7 | < 0.001 | 0.002 |
| Systolic BP (mmHg) | 315 | 167.0 | 18.4 | 154 | 169.6 | 17.1 | 80 | 118.6 | 9.0 | 22 | 119.1 | 11.9 | < 0.001 | < 0.001 |
| Diastolic BP (mmHg) | 316 | 105.7 | 10.1 | 154 | 105.1 | 10.4 | 80 | 73.6 | 7.8 | 22 | 72.2 | 8.9 | < 0.001 | < 0.001 |
| Birth weight (g) | 320 | 2399.9 | 934.6 | 162 | 2382.6 | 863.2 | 264 | 3537.8 | 404.0 | 185 | 3635.0 | 412.8 | < 0.001 | < 0.001 |
| Relative birth weight (SD) | 311 | -1.4 | 1.3 | 160 | -1.2 | 1.3 | 262 | -0.2 | 0.8 | 183 | 0.0 | 0.8 | < 0.001 | < 0.001 |
| Gestational age at birth (weeks) | 315 | 35.7 | 3.9 | 164 | 35.5 | 3.5 | 264 | 39.9 | 1.5 | 185 | 40.0 | 1.2 | < 0.001 | < 0.001 |
| N | % | N | % | N | % | N | % | p** | p** | |||||
| Gestational diabetes | 16 | 5.4 | 7 | 4.3 | 5 | 1.9 | 12 | 6.5 | 0.046 | 0.362 | ||||
| Pre-gestational diabetes | 8 | 2.7 | 5 | 3.1 | 1 | 0,0 | 1 | 0.5 | 0.046 | 0.103 | ||||
* Student's t-test or Mann-Whitney test. ** Chi-square test or Fisher's exact test