Table 2.
ACVR2A genotypes and allele counts among Finnish pre-eclampsia (PE) patients and control subjects combined from Finnish population based Data set (Data set 1), Southern Finland PE Data set (Data set 2) and Eastern Finland PE Data Set (Data set 3)
| Pre-eclampsia | Controls | p** | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Primiparous (n = 321) | Multiparous (n = 164) | Combined (n = 485) | Primiparous (n = 264) | Multiparous (n = 185) | Combined (n = 449) | Primiparous | Multiparous | Combined | |
| Genotypes | |||||||||
| GG | 134 | 67 | 201 | 108 | 87 | 195 | |||
| AG | 148 | 70 | 218 | 121 | 76 | 197 | |||
| AA | 32 | 24 | 56 | 33 | 21 | 54 | 0.468 | 0.660 | 0.871 |
| N/A* | 7 | 3 | 10 | 2 | 1 | 3 | |||
| Alleles (Frequency) | |||||||||
| G | 416 | 204 | 620 | 337 | 250 | 587 | |||
| A | 212 | 118 | 330 | 187 | 118 | 305 | 0.493 | 0.205 | 0.806 |
* Genotyping failed ** Chi-square test