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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: Free Radic Biol Med. 2011 Dec 8;52(4):803–810. doi: 10.1016/j.freeradbiomed.2011.11.025

Fig. 2. Effects of BSO treatment of juvenile mice on levels of components of the Trx- and GSH-pathways in livers.

Fig. 2

Juvenile (P23–25) wild-type (hepatocytes txnrd1+/+), txnrd1cond/+;albCre1 (hepatocytes txnrd1null/+), and txnrd1cond/null;albCre1 (hepatocytes txnrd1null/null) mice received an I.P. inoculation with saline alone (black bars) or 50 mg of BSO in sterile saline (open bars). Five hours later, mice were sacrificed and livers were perfused with saline and harvested for enzymatic analyses. Bars represent mean + S.E.M. for four mice in each condition. (A) Effects of BSO treatment on total TrxR activity. (B) Effects of BSO treatment on Trx levels. (C) Effects of BSO treatment on GSH + GSSG levels.