Table 1.

Demographics of children with childhood onset epilepsy by type of epilepsy and first degree family history of unprovoked seizure

Factor	Uncomplicated epilepsy1 (N=213)			Complicated epilepsy2 (N=95)
	Family history of unprovoked seizure (N=24)	No family history of unprovoked seizure (N=189)	p-value	Family history of unprovoked seizure (N=9)	No family history of unprovoked seizure (N=86)	p-value
Median age at onset (yrs)	5.0	6.0	0.4	5.0	6.0	0.4
Age at onset (yrs)
0 through 1	4 (16.6%)	41 (21.7%)		2 (22.2%)	30 (34.9%)
2 through 4	10 (41.7%)	60 (31.7%)		4 (44.4%)	33 (38.4%)
5 through 9	10 (41.7%)	88 (46.6%)		2 (22.2%)	23 (26.7%)
≥10	0 (0%)	0 (0%)	0.63	1 (11.1%)	0 (0%)	0.13
Age at interview
<10 Years	3 (12.5%)	24 (12.7%)		1 (11.1%)	19 (22.1%)
10 through 14 Years	14 (58.3%)	94 (49.7%)		6 (66.7%)	54 (62.8%)
15 through 19 Years	7 (29.2%)	71 (37.6%)		2 (22.2%)	13 (15.1%)	0.73
≥20 Years	0 (0%)	0 (0%)	0.63	0 (0%)	0 (0%)
Gender
Male	15 (55.2%)	99 (51.8%)		3 (33.3%)	52 (60.5%)
Female	9 (44.8%)	90 (48.2%)	0.43	6 (66.7%)	34 (39.5%)	0.23
Ever 5 year remission
Yes	16 (66.7%)	141 (74.6%)		5 (55.6%)	37 (43.0%)
No	8 (33.3%)	48 (25.4%)	0.53	4 (44.4%)	49 (57.0%)	0.53
Type of epilepsy
BECTS+	2 (8.3%)	44 (17.5%)		0 (0%)	2 (2.3%)
CAE	4 (16.7%)	38 (15.1%)		0 (0%)	7 (8.1%)
JAME	2 (8.3%)	18 (7.2%)		0 (0%)	0 (0%)
Other	16 (66.7%)	151 (60.2%)	0.053	9 (100%)	77 (89.5%)	1.03

¹Uncomplicated: Subject has cognitive function consistent with IQ >80 and no identified structural brain lesion or similar condition to which the epilepsy can be attributed.;

²Complicated: Subject has cognitive function level consistent with IQ<80 or there is a documented brain lesion or related condition to which the occurrence of epilepsy has been attributed;

³Fisher’s Exact Test