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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: Free Radic Biol Med. 2011 Dec 1;52(4):749–756. doi: 10.1016/j.freeradbiomed.2011.11.015

Figure 1.

Figure 1

Hydroperoxide activity in 8-oxoG base solution. (A) Concentration-dependent oxidation of Amplex red by 8-oxoG*. (B) Direct oxidation of AR by 8-oxoG* CHP and tBHP. H2O2 was used as a control. (C) 8-oxoG*, but not 8-oxoG or 8-oxodG oxidizes AR. (D) 8-oxoG*, but not Gua, 2-dG, 8-OHA, 8-oxodG, oxazolone or FapyG solution, has peroxide-like activity. Gua, guanine, 2-dG, 2-desoxyguanine; 8-OHA, 8-hydroxy adenine; 8-oxodG, 7,8- dihydro-8-oxo-2'-deoxyguanosine; FapyG, 2,6-diamino-4-hydroxy-5-formamidopyrimidine; CHP, cumene hydroperoxide; tBHP tert-butyl hydroperoxide. Results are means ±SEM (n=5-11).