Table 2.
Residues of antibiotics in the heart valve allograft tissue (second phase)
| Antibiotic | Tissue | Antibiotics residues detected by HPLC in tested tissue, μg/g | Residual antibiotics based on initial concentration in MEM 199, % |
|---|---|---|---|
| Vancomycin HC1 | AV (nr) | 18.14 | 0.88 |
| AV(r) | 10.74 | 0.65 | |
| PV (nr) | 16.67 | 1.01 | |
| PV(r) | 11.92 | 0.72 | |
| Lincomycin HC1 | AV (nr) | 6.72 | 0.14 |
| AV(r) | 8.44 | 0.21 | |
| PV (nr) | 7.58 | 0.19 | |
| PV(r) | 8.68 | 0.22 | |
| Polymyxin B | AV (nr) | 0.00 | 0.00 |
| AV(r) | 0.00 | 0.00 | |
| PV (nr) | 0.00 | 0.00 | |
| PV(r) | 0.00 | 0.00 |
AV = Aortic valve; PV = pulmonary valve; nr = not rinsed; r = rinsed.