Table 5.
Risk of SVTE according to TWA status in patient subgroups
| Subgroups | Events/n (%) | Hazard ratio (95% CI) | Interaction P* |
|---|---|---|---|
| Age | 0.09/0.20 | ||
| <65 years | |||
| TWA-negative | 1/46 (2.2%) | ||
| TWA-non-negative | 13/91 (14.3%) | 7.69 (1.01–58.8) | |
| Ineligible for TWA | 12/58 (20.7%) | 11.21 (1.46–86.2) | |
| ≥65 years | |||
| TWA-negative | 1/36 (2.8%) | ||
| TWA-non-negative | 6/107 (5.6%) | 1.92 (0.23–16.0) | |
| Ineligible for TWA | 14/115 (12.2%) | 4.44 (0.58–33.8) | |
| Etiology of LV dysfunction | 0.19/0.10 | ||
| Ischemic | |||
| TWA-negative | 2/41 (4.9%) | ||
| TWA-non-negative | 8/94 (8.5%) | 1.87 (0.40–8.79) | |
| Ineligible for TWA | 6/54 (11.1%) | 2.38 (0.48–11.8) | |
| Non-ischemic | |||
| TWA-negative | 0/41 (0%) | ||
| TWA-non-negative | 11/104 (10.6%) | –a | |
| Ineligible for TWA | 20/119 (16.8%) | –a | |
| LVEF | 0.19/0.05 | ||
| ≤35% | |||
| TWA-negative | 1/63 (1.6%) | ||
| TWA-non-negative | 17/160 (10.6%) | 7.06 (0.94–53.09) | |
| Ineligible for TWA | 23/130 (17.7%) | 12.52 (1.69–92.74) | |
| >35% | |||
| TWA-negative | 1/19 (5.3%) | ||
| TWA-non-negative | 2/38 (5.3%) | 1.06 (0.14–12.51) | |
| Ineligible for TWA | 3/43 (7.0%) | 1.30 (0.10–11.71) | |
| QRS duration | 0.46/0.05 | ||
| ≥120 ms | |||
| TWA-negative | 0/24 (0%) | ||
| TWA-non-negative | 7/72 (9.7%) | –a | |
| Ineligible for TWA | 20/103 (19.6%) | –a | |
| <120 ms | |||
| TWA-negative | 2/58 (3.4%) | ||
| TWA-non-negative | 12/126 (9.5%) | 2.91 (0.51–12.6) | |
| Ineligible for TWA | 6/70 (8.6%) | 2.51 (0.65–13.0) | |
* P for interaction between TWA and each variable based on difference in probabilities of events; TWA-negative versus TWA-non-negative (left) and TWA-negative versus ineligible for TWA (right)
aIndeterminate because of no events in TWA-negative group