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Western blot of TH and GAD67 in the PVN showed that HF rats had higher levels of TH and lower levels of GAD67 when compared with SHAM rats. Bilateral PVN infusions of SN50 for 4 weeks decreased expression of TH, and increased GAD67 expression in the PVN of HF rats. *P<0.05 versus SHAM groups. †P<0.05 HF+PVN SN50 versus HF+PVN vehicle.
