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. Author manuscript; available in PMC: 2012 Nov 1.

Published in final edited form as: Basic Res Cardiol. 2011 Sep 4;106(6):1087–1097. doi: 10.1007/s00395-011-0215-7

Table 2.

Proinflammatory cytokines in the PVN and plasma (n=7)

Measurements at 4-weeks	PVN (pg/mg protein)			Plasma (pg/ml)
Measurements at 4-weeks	TNF-α	IL-1β	IL-6	TNF-α	IL-1β	IL-6	ANG II
HF + PVN SN50	4.0±0.4^†	21.6±2.6^†	26.5±2.5^†	13.2±1.4^†	68.6±6.2^†	45.3±4.2^†	67.4±5.9^†
HF + PVN SN50M	7.5±0.6^*	53.4±4.7^*	65.4±6.1^*	37.4±3.5^*	119.8±10.7^*	101.7±9.6^*	123.8±10.3^*
HF + PVN vehicle	7.7±0.6^*	55.1±4.8^*	67.1±6.2^*	38.2±3.6^*	121.7±10.8^*	103.4±9.8^*	126.3±10.5^*
SHAM + PVN SN50	3.5±0.4	17.3±1.5	19.2±1.9	10.6±1.3	56.4±4.6	37.4±3.9	57.5±4.7
SHAM + PVN SN50M	3.6±0.4	18.7±2.2	23.6±2.0	11.7±1.4	60.9±5.8	40.8±4.1	61.8±5.2
SHAM + PVN vehicle	3.7±0.4	19.4±2.3	25.1±2.2	12.2±1.4	63.7±5.7	43.1±4.0	64.1±5.4

^*

P<0.05 versus SHAM groups.

^†

P<0.05 HF+PVN SN50 versus HF+PVN vehicle or HF+PVN SN50M.