Table 3.

Hemodynamic and anatomical measurements (n=7)

Measurements at 4-weeks	RV/BW (mg/g)	Lung/BW (mg/g)	HR (beats/min)	MAP (mmHg)	PP (mmHg)	LVEDP (mmHg)
HF + PVN SN50	0.78±0.08†	5.6±0.4†	337±12	98±7	31±4	17.72±1.31†*
HF + PVN SN50M	1.17±0.10*	10.8±0.6*	340±13	97±7	34±5	23.81±1.80*
HF + PVN vehicle	1.20±0.11*	11.2±0.6*	342±13	95±6	33±5	23.74±1.82*
SHAM + PVN SN50	0.61±0.05	4.7±0.4	332±11	105±8	35±4	6.14±1.59
SHAM + PVN SN50M	0.66±0.05	5.0±0.4	330±13	108±9	34±5	6.53±1.42
SHAM + PVN vehicle	0.69±0.06	5.3±0.5	335±12	107±9	36±5	7.05±1.56

SHAM: sham-operated control; HF: heart failure; BW: body weight; RV: right ventricular; HR: heart rate; MAP: mean arterial pressure; PP: pulse pressure; LVEDP: left ventricular end-diastolic pressure. Values are mean±SEM.

^*P<0.05 versus SHAM groups.

^†P<0.05 HF+PVN SN50 versus HF+PVN vehicle or HF+PVN SN50M.