Table 1.
Baseline and Post-Infarct Remodeling
| Baseline (n = 6) | Early (n = 6) | Late (n = 6) | p-value | |
|---|---|---|---|---|
| Days after MI | - | 10 ± 2 | 34 ± 10 | NA |
| Heart rate (bpm) | 89 ± 8 | 74 ± 9 | 77 ± 15 | NS |
| LVEF (%) | 52 ± 5 | 44 ± 7 | 45 ± 4 | < 0.01 |
| LVEDD (mm) | 38 ± 2 | 40 ± 3 | 41 ± 3 | NS |
| RVEDD (mm) | 24 ± 2 | 26 ± 2 | 27 ± 2 | NS |
| LVEDV (mL) | 42 ± 7 | 56 ± 10 | 65 ± 9 | < 0.01 |
| LVESV (mL) | 20 ± 5 | 31 ± 7 | 36 ± 12 | < 0.01 |
| MI segment thickness (mm) | - | 6 ± 1 | 5 ± 1 | < 0.01 |
| Normal segment thickness (mm) | 9 ± 1 | 10 ± 0 | 12 ± 2 | NS |
| Late gadolinium enhancement % | - | 21 ± 4 | 20 ± 6 | NS |
EF = ejection fraction; EDD = end diastolic dimension; EDV and ESV = end-diastolic and end-systolic volumes, respectively. All p-values relate to early and late versus baseline except where baseline values are absent.