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. Author manuscript; available in PMC: 2012 Nov 9.
Published in final edited form as: J Am Chem Soc. 2011 Oct 18;133(44):17641–17651. doi: 10.1021/ja2046149

Figure 4.

Figure 4

Effect of daunomycin on DNA alkylation by activated leinamycin. Mixtures of daunomycin, leinamycin, and 2-mercaptoethanol were incubated with DNA as described in the Legend of Figure 3. The plot shows the total yield of deoxyguanosine alkylation in each lane versus Log daunomycin concentration.