Figure 7.

PGE₂-induced increase in frequency of WCTs is abolished by nifedipine and reduced by NF449. (A) WCTs after the addition of PGE₂ (50 µM) alone and in the presence of nifedipine (1 µM). The spikes on the trace represent WCTs, against time, in one preparation. (B) The frequency of WCTs after superfusion with PGE₂ (50 µM) in the presence and absence of NF449 (10 µM). Each trace is a concatenated composite of shorter 13.7 s recording segments taken every minute. (C) A comparison of the frequency of WCTs under different conditions. *P < 0.05 and **P < 0.01.