Table 1.

Descriptive statistics of the effects of PGE₂ and the purinoceptor P2X1 antagonist NF449 (10 µM) on properties of SMCs and their spontaneous depolarizations (sDep)

	Treatment			Paired t-test, P
	Control	PGE2 (50 µM)	PGE2 (50 µM) + NF449 (10 µM)	PGE2+ NF449 vs. control	PGE2+ NF449 vs. PGE2
RMP (mV)	−40.0 [−46.9 to −35.9]	−29.9 [−32.0 to −25.3]	−29.6 [−32.0 to −26.7]	<0.05	NS
sDep
Frequency (Hz)	0.5 [0.2–0.8]	0.6 [0.6–1.4]	0.7 [0.6–1.4]	<0.05	NS
Amplitude (mV)	4.6 [3.6–8.6]	6.3 [4.6–13.9]	5.5 [4.0–10.9]	NS	NS
Interval (s)	1.6 [1.1–3.8]	0.9 [0.6–1.3]	0.9 [0.6–1.1]	NS (0.07)	NS
Rise time (ms)	19 [11–66]	48 [20–90]	67 [37–96]	<0.05	<0.05
No. events	724 [304–951]	736 [453–888]	688 [286–1023]	–	–
na	4	4	4	4	4

Data shown are median [range]. n_a, number of animals. NS denotes P > 0.05.