Table 2. Percent multiple innervation in thy1-YFP-lineH EOM muscles during postnatal development.
EOM muscle | % Multiple innervation at various postnatal ages | |||||
---|---|---|---|---|---|---|
P5 | P7 | P11 | P14 | P21 | P56 | |
Superior Rectus (SR) muscle | 100% (N=2, n=19) | 79.5 ± 9.2% (N=11, n=319) | 4.8 ± 3.4% (N=7, n=243) | 2.2 ± 2.8% (N=12, n=269) | ND | 1.0± 1.0% (N=9, n=121) |
Superior Oblique (SO) muscle | 100% (N=1, n=8) | 77.6 ± 6.7% (N=7, n=175) | 6.9 ± 1.4% (N=7, n=243) | 7.5 ± 3.7% (N=12, n=269) | ND | ND |
Lateral Rectus (LR) muscle | ND | 84.8 ± 10.5% (N=5, n=75) | 7.7 ± 4.4% (N=7, n=243) | 3.8 ± 3.6% (N=12, n=269) | ND | ND |
Levator Palpebrae Superioris (LPS) muscle | 100% (N=1, n=5) Not statistically different than P5 SR or SO muscles |
87.0 ± 7.7% (N=7, n=120) Not statistically different than P7 SR, SO, or LR muscles |
45.1 ± 4.1% (N=8, n=151) *p<0.0001 vs P11 SR, SO and LR muscles |
42.7 ± 6.6% (N=6, n=106) *p<0.0002 vs P14 SR, SO and LR muscles |
22.1 ± 9.1% (N=5, n=103) *p<0.004 vs P14 SR, SO, LR, and LPS muscles |
7.3± 2.5% (N=8, n=80) *p<0.05 vs P56 SR muscle |