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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: J Comp Neurol. 2011 Oct 15;519(15):2907–2921. doi: 10.1002/cne.22700

Table 2. Percent multiple innervation in thy1-YFP-lineH EOM muscles during postnatal development.

Numbers of multiply innervated ‘en plaque’-type NMJs were counted in SR, SO, LR, and LPS muscles throughout development. Each percentage represents the percent of multiply innervated synapses (±SD). N = the number of muscles analyzed per age; n = the total number of NMJs analyzed per age; ND – not determined. Tukey-Kramer tests were performed on data obtained from all age-matched muscles. For P21 LPS muscles, data was compared against all EOMs at P14. All statistically significant data sets are highlighted with asterisks and p values. For comparison with rates of synapse elimination in somite-derived muscles in thy1:yfp-lineH mice see Keller-Peck et al. 2001.

EOM muscle % Multiple innervation at various postnatal ages
P5 P7 P11 P14 P21 P56
Superior Rectus (SR) muscle 100% (N=2, n=19) 79.5 ± 9.2% (N=11, n=319) 4.8 ± 3.4% (N=7, n=243) 2.2 ± 2.8% (N=12, n=269) ND 1.0± 1.0% (N=9, n=121)
Superior Oblique (SO) muscle 100% (N=1, n=8) 77.6 ± 6.7% (N=7, n=175) 6.9 ± 1.4% (N=7, n=243) 7.5 ± 3.7% (N=12, n=269) ND ND
Lateral Rectus (LR) muscle ND 84.8 ± 10.5% (N=5, n=75) 7.7 ± 4.4% (N=7, n=243) 3.8 ± 3.6% (N=12, n=269) ND ND
Levator Palpebrae Superioris (LPS) muscle 100% (N=1, n=5)
Not statistically different than P5 SR or SO muscles
87.0 ± 7.7% (N=7, n=120)
Not statistically different than P7 SR, SO, or LR muscles
45.1 ± 4.1% (N=8, n=151)
*p<0.0001 vs P11 SR, SO and LR muscles
42.7 ± 6.6% (N=6, n=106)
*p<0.0002 vs P14 SR, SO and LR muscles
22.1 ± 9.1% (N=5, n=103)
*p<0.004 vs P14 SR, SO, LR, and LPS muscles
7.3± 2.5% (N=8, n=80)
*p<0.05 vs P56 SR muscle