Fig. 6.
Mouse model of biofilm-associated infection. Two catheter pieces coated with the same strain of USA300 (LAC) WT or isogenic psm mutant bacteria (∼3 × 105 cfu per catheter piece) were inserted in the left and right dorsum of Nu/Nu mice. At day 7, mice were euthanized, and disseminated bacteria were counted. Samples with considerable bacterial numbers are shown. Only very small numbers of bacteria were found in the organs. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 vs. LAC (one-way ANOVA with Bonferroni posttests).