TABLE 1.

M-mode echocardiography data

LVDD, left ventricular diastolic dimensions; FS, fractional shortening; NS, significant.

	LVDD	FS	p value
	mm	%
Sham-operated	0.45 ± 0.02	61 ± 3.7	NS
Renal artery-ligated (Ligated)	0.54 ± 0.04	43 ± 2.5	p < 0.05 vs. sham
Ligated + DMSO	0.55 ± 0.05	41 ± 2.6	NS vs. ligated
Ligated + S31-201	0.47 ± 0.01	54 ± 2.9	p < 0.05 vs. ligated + DMSO
Ligated + nonspecific siRNA	0.53 ± 0.06	42 ± 2.8	NS vs. ligated
Ligated + STAT3siRNA	0.46 ± 0.02	55.6 ± 3.2	p < 0.05 vs. ligated + nonspecific siRNA