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. 2011 Oct 6;9:e0144. doi: 10.1199/tab.0144

Figure 52.

Figure 52.

The reactions catalyzed by yeast-expressed CYP703A2.

Yeast-expressed CYP703A2 catalyzes a single hydroxylation of medium chain fatty acids, mainly C12:0 and C10:0, in the chain with C7 as the main but not exclusive position of hydroxylation. Hydroxylated products obtained decrease with the distance from C7 as indicated by the size of the arrows on the top of the chain that roughly reflect reaction efficiency. A more specific reaction might occur in vivo.