Figure 1.
Chemical structure of 20-HETE and 20-5,14-HEDGE. (b and c) IR lungs from vehicle-and 20-5,14-HEDGE-treated rats. IR resulted in gross hemorrhage in the left, and to a lesser extent, right lungs. Treatment with 20-5,14-HEDGE decreased visible hemorrhage. (d,e) H&E sections revealed hemorrhage (arrows point to RBCs in intra-alveolar spaces) in ischemic left lungs which exceeded that in right lungs.