Table A2.

Ribosomal protein genes in kidneys of FHH males differentially expressed by molsidomine (FM, 2 days and 2 weeks) or after perinatal molsidomine (FM, adult) vs. controls (FC).

Entrez gene ID	Ribosome	Chromosome	Gene expression
			2 Days	2 Weeks	Adult
A: 2 DAYS
366411	S24	5	0.820	−0.217	−0.354
500817	S20	7	0.723	−0.317	−0.409
287029	L31	10	0.709	−0.399	−0.642
501876	L36a	13	0.680	−0.424	−0.383
289384	L37	13	0.632	−0.192	−0.844
500451	S20	5	0.534	−0.114	−0.452
367923	L23a	3	0.503	−0.394	−0.403
314434	L9	X	0.488	−0.436	−0.369
680294	L19	–	0.485	−0.312	−0.510
502887	L31	4	0.470	−0.397	−0.523
500322	S7	4	0.462	−0.192	−0.411
500510	L21	5	0.437	−0.044	−0.432
498078	L7a	11	0.427	−0.331	−0.354
364108	S17	14	0.418	−0.517	−0.490
294700	L21	2	0.409	−0.434	−0.293
287417	L26	10	0.399	−0.228	−0.253
295439	L21	2	0.353	−0.334	−0.175
314733	S19	7	0.329	−0.330	−0.638
289715	L37	14	0.314	−0.454	−0.554
364059	L34	13	0.299	−0.352	−0.662
365800	L36a	4	0.280	−0.014	−0.131
498828	L10	18	0.276	−0.241	−0.306
364825	L36	18	−0.199	0.117	0.126
B: 2 WEEKS
362216	S26	3	−0.154	0.427	−0.330
308719	L27a	1	−0.068	0.243	0.044
503211	L21	8	−0.051	0.161	0.111
367030	SA	8	0.106	0.155	−0.061
287417	L26	10	0.399	−0.228	−0.253
298126	L31	5	0.018	−0.261	−0.566
313283	S12	5	0.045	−0.279	−0.548
287996	L21	11	−0.022	−0.281	0.002
296870	L34	X	−0.008	−0.295	−0.283
364828	L29	18	0.132	−0.297	−0.506
500559	S20	5	0.132	−0.302	−0.188
498360	S23	14	0.033	−0.304	−0.164
680294	L19	–	0.485	−0.312	−0.510
500817	S20	7	0.723	−0.317	−0.409
367102	S9	8	−0.068	−0.325	−0.458
299935	L31	7	0.001	−0.328	−0.461
295439	L21	2	0.353	−0.334	−0.175
364059	L34	13	0.299	−0.352	−0.662
300731	L21	8	0.061	−0.352	−0.638
499133	L27a	1	0.119	−0.363	−0.477
687298	S19	10	0.059	−0.365	−0.541
366656	L10a	6	0.188	−0.370	−0.260
502854	L31	4	0.166	−0.376	−0.624
297755	L7	5	0.252	−0.386	−0.308
294781	L21	2	0.397	−0.388	−0.627
65139	S12	1	0.225	−0.393	−0.765
367923	L23a	3	0.503	−0.394	−0.403
287029	L31	10	0.709	−0.399	−0.642
501604	L7a	X	0.287	−0.402	−0.218
81772	S9	1	0.252	−0.406	−0.620
289401	L31	13	0.243	−0.424	−0.735
501876	L36a	13	0.680	−0.424	−0.383
299740	L31	7	−0.024	−0.426	−0.539
294700	L21	2	0.409	−0.434	−0.293
314434	L9	X	0.488	−0.436	−0.369
300278	S9	X	0.414	−0.436	−0.590
289715	L37	14	0.314	−0.454	−0.554
498744	L37	17	0.151	−0.454	−0.851
501058	S23	8	0.054	−0.467	−0.297
363418	L17	12	0.068	−0.469	−0.316
81770	L37	2	−0.136	−0.472	−0.618
500817	S20	7	0.080	−0.484	−0.347
363861	L29	12	0.212	−0.490	−0.467
366887	L31	7	0.379	−0.497	−0.497
686564	L23a	14	0.520	−0.497	−0.446
364139	L21	14	0.150	−0.497	−0.758
364108	S17	14	0.418	−0.517	−0.490
29258	S7	5	−0.076	−0.520	−0.650
500019	L29	4	−0.300	−0.666	−0.375
C: 36 WEEKS
360710	L7a	11	0.034	0.157	0.218
365300	L7	1	−0.007	0.004	−0.213
294282	S18	20	−0.094	−0.010	−0.337
498837	S27a	18	0.196	−0.043	−0.342
315521	L32	8	0.339	0.010	−0.363
367250	L7a	9	0.021	0.060	−0.371
365560	L36a	20	0.030	−0.097	−0.384
500451	S20	5	0.534	−0.114	−0.452
367102	S9	8	−0.068	−0.325	−0.458
299935	L31	7	0.001	−0.328	−0.461
499133	L27a	1	0.119	−0.363	−0.477
500559	S20	5	0.220	−0.339	−0.490
309408	S12	1	−0.079	−0.134	−0.495
498954	S16	19	0.099	−0.171	−0.499
302497	L10a	X	0.334	−0.262	−0.499
25347	L39	X	0.014	−0.145	−0.512
302898	L1	10	0.034	0.076	−0.515
302528	L37a	X	0.006	−0.041	−0.520
502887	L31	4	0.470	−0.397	−0.523
499752	L7a	3	0.115	−0.093	−0.527
124323	S23	2	0.163	−0.260	−0.529
293754	L16	1	−0.278	0.116	−0.548
313283	S12	5	0.045	−0.279	−0.548
289715	L37	14	0.314	−0.454	−0.554
315642	L27a	8	−0.162	−0.126	−0.560
298495	L35a	5	0.296	−0.332	−0.565
298126	L31	5	0.018	−0.261	−0.566
366689	L21	6	−0.128	−0.317	−0.575
81768	L22	5	0.002	−0.148	−0.580
300278	S9	X	0.414	−0.436	−0.590
292539	L17	1	0.237	−0.246	−0.592
498363	P2	14	0.481	−0.130	−0.597
299041	P1	X	0.041	−0.157	−0.601
57809	L35a	1	−0.112	−0.210	−0.614
81772	S9	1	0.252	−0.406	−0.620
502854	L31	4	0.166	−0.376	−0.624
294781	L21	2	0.397	−0.388	−0.627
314054	S10	6	−0.053	−0.170	−0.631
314733	S19	7	0.329	−0.330	−0.638
287029	L31	10	0.709	−0.399	−0.642
498555	P2	15	0.002	−0.072	−0.645
503110	S19	7	0.008	−0.047	−0.651
64360	L23	1	−0.247	0.029	−0.654
297459	S25	4	−0.247	0.160	−0.659
314248	S17	6	0.000	−0.064	−0.661
364059	L34	13	0.299	−0.352	−0.662
171061	L17	1	0.219	−0.170	−0.663
366485	–	5	−0.275	−0.376	−0.665
500714	L6	6	0.023	−0.218	−0.686
289401	L31	13	0.243	−0.424	−0.735
27139	S26	7	0.205	−0.240	−0.760
65139	S12	1	0.225	−0.393	−0.765
498523	L23a	15	−0.134	−0.253	−0.766
289932	S7	15	0.098	−0.295	−0.785
502302	S19	1	0.002	−0.034	−0.796
289384	L37	13	0.632	−0.192	−0.844
498744	L37	17	0.151	−0.454	−0.851
367077	S26	8	0.170	−0.348	−0.852
299848	S26	7	0.029	−0.217	−0.882

All genes that are significantly differentially expressed by molsidomine are arranged per age [(A) is newborn males, i.e., 2 days, (B) is 2-week-old males, and (C) is adult males, i.e., 36 weeks]. The difference in gene expression between molsidomine-treated and control FHH was noted as Log₂(FM/FC), where FM and FC are the normalized intensities. Red and blue numbers indicate gene expression differentially induced and reduced by molsidomine, respectively. The symbols and the chromosomal locations are also shown. Ratios indicated in bold and red are increased differential expression and ratios indicated in bold and blue are decreased differential expression. Note that some genes in (A) may reappear in (B,C) and some genes in Table A2B may reappear in Table A2C.