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. 2011 Nov 21;2:80. doi: 10.3389/fgene.2011.00080

Table A1.

Penetrance functions for one-locus dominant main effect models.

One-locus dominance models
OR Models (#) MAF = 0.2
 Models (#) MAF = 0.4
AA Aa Aa AA Aa Aa
1.2 (1) h2 = 1.05% 0.0155 0.0155 0.012916 (2) h2 = 1.07% 0.0155 0.0155 0.012916
1.4 (3) h2 = 1.01% 0.0159 0.0159 0.011349 (4) h2 = 1.07% 0.0155 0.0155 0.01108
1.6 (5) h2 = 1.04% 0.017 0.017 0.010625 (6) h2 = 1.1% 0.016 0.016 0.009999
1.8 (7) h2 = 1.02% 0.017 0.017 0.009444 (8) h2 = 1.09% 0.016 0.016 0.008879
2.0 (9) h2 = 1.013% 0.017 0.017 0.0085 (10) h2 = 1.03% 0.015 0.015 0.0075
2.0 (11) h2 = 5.00% 0.083 0.083 0.041489 (12) h2 = 5.007% 0.072 0.072 0.035989
2.5 (13) h2 = 5.03% 0.0833 0.0833 0.03332 (14) h2 = 5.066% 0.072 0.072 0.0288
3.0 (15) h2 = 5.07% 0.08233 0.08233 0.02744 (16) h2 = 5.07% 0.071 0.071 0.02366

(#), Model numbers; OR, odds ratio; MAF, minor allele frequency; h2, heritability; values in the center of the table represent the probability of disease given the genotype.