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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Free Radic Biol Med. 2011 Nov 12;52(3):699–704. doi: 10.1016/j.freeradbiomed.2011.11.004

Figure 1.

Figure 1

Localization of fluorophore immunoreactivity is increased in AD pyramidal neurons (B) as compared to an age-matched control (A). Densitometric analysis of the pyramidal neuron levels of fluorophore, shows significantly higher levels in the AD cases (n=10) compared to age-matched controls (n=7) (p<0.01, C). In the AD cases, many neurons contained intensely labeled GVD structures (B, and higher magnification in E) and some cases demonstrated labeling of Hirano bodies (D). Scale bar for A,B,D = 50 μm; E = 20 μm.