Table 3.
Data analysis of the clinical neurological damage caused by different pathogens
| EV71 | CA16 | OE | p value | Total | |
|---|---|---|---|---|---|
| Total (n) | 65(70.7%) | 19(20.7%) | 8(8.7%) | 92 | |
| Encephalitis (n)# | 39(60%) | 16(82.4%) | 6(75%) | 0.125 | 61(66.3%) |
| Acute flaccid paralysis (n)# | 2(3%) | 1(5.3%) | 0 | 0.772 | 3(3.3%) |
| Brainstem encephalitis (n)# | 8(12.3%) | 2(1.1%) | 0 | 0.572 | 10(10.9%) |
| Neurogenic pulmonary edema (n)# | 11(16.9%) | 0 | 1(12.5%) | 0.047 | 11(12%) |
| Neurologic shock (n)# | 5(7.7%) | 0 | 1(12.5%) | 0.215 | 6(6.5%) |
| Limb shaking (n) | 51(78.5%) | 15(78.9%) | 6(75%) | 0.973 | 72(78.3%) |
| Convulsion (n) | 21(32.3%) | 4(21.1%) | 2(25%) | 0.613 | 27(29.3%) |
| Vomiting (n) | 42(64.6%) | 16(84.2%) | 7(87.5%) | 0.141 | 65(70.7%) |
| Fatigue (n) | 47(72.3%) | 17(89.5%) | 5(62.5%) | 0.219 | 69(75%) |
| Coma (n) | 24(36.9%) | 2(10.5%) | 1(12.5%) | 0.046 | 27(29.3%) |
| Limb movement disorder (n) | 34(52.3%) | 3(15.8%) | 2(25%) | 0.010 | 39(42.4%) |
| Urinary retention (n) | 31(47.7%) | 6(31.6%) | 2(25%) | 0.266 | 39(42.4%) |
| CSFWBC > 10 × 106/L (n)§ | 21/44(47.7%) | 8/14(57.1%) | 3/6(50%) | 0.828 | 25/64(39.1%) |
| CSFPro ≥ 0.5 g/L (n)§ | 15/44(34.1%) | 5/14(35.7%) | 2/6(33.3%) | 0.992 | 22/64(34.4%) |
| Ambulatory EEG abnormality (n)§ | 17/32(53.1%) | 4/13(30.8%) | 1/5(20%) | 0.205 | 22/50(44%) |
| Head MRI abnormality (n)§ | 13/32(40.6%) | 5/15(33.3%) | 2/6(33.3%) | 0.685 | 20/53(37.7%) |
| Patients with dysfunction upon discharge (n) | 11(16.9%) | 1(5.3%) | 1(12.5%) | 0.435 | 13(14.1%) |
| Death (n)¤ | 5(7.7%) | 0 | 0 | 0.333 | 5(5.4%) |
# There was no repeat counting in calculating the distribution of disease types. When neurogenic pulmonary edema or shock and brain stem encephalitis coexisted in the same patient, the former was counted. When neurogenic shock and pulmonary edema coexisted, pulmonary edema was counted. §The denominator of the fraction represents the cases examined, whereas the numerator represents the number of patients with this abnormality. ¤Among the 5 fatal cases, 2 died of neurogenic pulmonary edema, 2 died of shock and 1 patient was declared brain-dead