Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Feb 1;23(3):464–479. doi: 10.1091/mbc.E11-07-0590

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 Welte et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

“ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell Biology.

PMC Copyright notice

FIGURE 5: — Membrane protein integration via YidC is restricted to membrane proteins with small periplasmic loops. (A) Predicted topology of YidC. The cleavage site for PK is indicated. The YidC-MPF corresponds to the first two TMs and the connecting periplasmic loop (Koch et al., 2002). (B) YidC was synthesized in presence of SRP, FtsY, and liposomes/proteoliposomes as indicated. Protease protection was analyzed in the absence or presence of 600 nM SecA. Full-length YidC and YidC-MPFs are indicated. (C) Predicted topology of YidCΔ307 (Deitermann et al., 2005). (D) Protease protection of YidCΔ307. The lower, 13-kDa MPF was used for calculating integration rates. (E) Protease protection of YidCΔ307 in the presence of proteoliposomes containing wild-type YidC or the YidC(I361S) mutant.