Table 5.
Genotyping results for rs2941504.
| Genetic Model | Genotype/Alleled | Affectede | Unaffectedf | P valueg | OR | 95% CIh | |
|---|---|---|---|---|---|---|---|
| General | GG/AG/AA | 93/449/467 | 170/432/410 | 1.48 × 10-6 | 0.526 0.480 |
(0.396-0.700) (0.361-0.639) |
|
| Multiplicative | G/A | 635/1383 | 772/1252 | 9.56 × 10-6 | 0.745 | (0.654-0.848) | |
|
1011 vs |
Additive | G/A | 635/1383 | 772/1252 | 1.25 × 10-5 | 0.745 | (0.654-0.848) |
| 1014a | Dominant | GG+AG/AA | 542/467 | 602/410 | 9.25 × 10-3 | 0.790 | (0.663-0.943) |
| Recessive | GG/AG+AA | 93/916 | 170/842 | 4.34 × 10-7 | 0.503 | (0.384-0.658) | |
|
1011 vs |
General | GG/AG/AA | 93/449/467 | 163/644/570 | 2.25 × 10-2 | 0.818 0.696 |
(0.617-1.085) (0.525-0.924) |
| 1445b | Multiplicative | G/A | 635/1383 | 970/1784 | 6.97 × 10-3 | 0.845 | (0.747-0.954) |
|
1445 vs |
General | GG/AG/AA | 163/644/570 | 170/432/410 | 1.96 × 10-3 | 0.643 0.690 |
(0.502-0.823) (0.537-0.885) |
| 1014c | Multiplicative | G/A | 970/1784 | 772/1252 | 3.87 × 10-2 | 0.882 | (0.783-0.993) |
a) Genotyping results for 1011 case versus 1014 control samples comparison; b) Genotyping results for 1011 case versus 1445 atopic samples comparison; c) Genotyping results for 1445 atopic versus 1014 control samples comparison; d) Order of genotype and/or allele counts listed in columns e) and f); g) P values from a Fisher's test using a 3 × 2 table for General genetic model, a 2 × 2 table for Multiplicative, Dominant or Recessive models, and P value from a Cochran Armitage Trend test for Additive model; h) Odds ratio and 95% confidence interval calculated for the AG and AA genotypes respectively using GG as the reference under the General model, for the A allele using G as the reference under the Multiplicative and Additive models, for the AA genotype using GG and AG as the reference under the Dominant model, and for the AG and AA genotypes using GG as the reference under the Recessive model.