Table 2. The levels of chemokines in cerebrospinal fluid (CSF) and plasma obtained at baseline.
CSF | Controls n = 30 | Stable MCI n = 52 | MCI-AD n = 47 | MCI-other n = 20 |
CCL2 | 649±182 | 676±183 | 684±194 | 729±176 |
CCL11 | 11±4 | 12±4 | 12±5 | 12±5 |
CCL13 | 14±10 | 12±10 | 16±13 | 20±29 |
CCL26 | 14±19 | 33±55 | 33±48a | 16±20 |
The chemokine levels are given in pg/ml. Only P-values<0.01 are considered significant, because of correction for multiple comparisons (all groups were compared to both controls and stable MCI).
P<0.01 vs Controls.
P<0.01 vs Stable MCI.
Abbreviations: Stable MCI, patients with MCI with stable cognitive functions during a follow-up period of 5.2 years; MCI-AD, patients with MCI who developed Alzheimer's disease during follow-up; MCI-other, patients with MCI who developed other types of dementia during follow-up; CSF, cerebrospinal fluid.