Table 5. Performance comparisons for human protein subcellular location prediction method based on the Hum3681 dataset.
Subcellular location | Hum-mPLoc 2.0 (2009) (Shen and Chou 2009) | LIBSVM | KNN | The proposed method | |||
Jackknife | Jackknife | Jackknife | Jackknife | ||||
Accuracy (%) | Accuracy (%) | MCC | Accuracy (%) | MCC | Accuracy (%) | MCC | |
Centriole | - | 93.51 | 0.9240 | 93.51 | 0.8867 | 94.81 | 0.9249 |
Cytoplasm | - | 39.66 | 0.9151 | 91.43 | 0.7218 | 41.37 | 0.9007 |
Cytoskeleton | - | 51.90 | 0.8138 | 8.86 | 0.8816 | 51.90 | 0.8232 |
Endosome | - | 54.17 | 0.7012 | 33.33 | 0.7552 | 54.17 | 0.7417 |
Endoplasmic reticulum | - | 78.85 | 0.9046 | 79.30 | 0.8960 | 78.85 | 0.9043 |
Extracell | - | 86.23 | 0.9705 | 82.60 | 0.9029 | 86.23 | 0.9689 |
Golgi apparatus | - | 70.19 | 0.8853 | 39.75 | 0.9284 | 70.19 | 0.8887 |
Lysosome | - | 93.51 | 0.9407 | 57.14 | 0.9777 | 93.51 | 0.9407 |
Microsome | - | 50.00 | 0.8008 | 0.00 | - | 50.00 | 0.8008 |
Mitochondrion | - | 84.89 | 0.9569 | 81.04 | 0.9763 | 83.79 | 0.9596 |
Nucleus | - | 91.67 | 0.8876 | 50.15 | 0.9833 | 91.77 | 0.8932 |
Peroxisome | - | 97.87 | 0.9380 | 51.06 | 0.9605 | 97.87 | 0.9481 |
Plasma membrane | - | 84.66 | 0.8887 | 60.80 | 0.9618 | 84.66 | 0.8870 |
Synapse | - | 86.36 | 0.8487 | 27.27 | 0.8657 | 86.36 | 0.8487 |
Overall accuracy | 62.7 | 75.22 | - | 67.75 | - | 75.55 | - |
- | 72.22 | - | 65.19 | - | 72.25 | - |