Table 1.

Summary of results.

Loading type	ATP release	Gene expression	Number of samples
A: Turbulent fluid flow in monolayer	Rapid increase	Increased c-fos, decreased Cox-2	18 (3 independent experiments, 6 replicates per experiment)
B: Turbulent fluid flow in 3D	Large and rapid increase	Large increase in c-fos	23 (5 independent experiments, 4 to 6 replicates per experiment)
C: Laminar fluid flow	Gradual increase	No change in c-fos	6 (3 independent experiments, 2 replicates per experiment)
D: Substrate strain	Gradual increase	Large increase in c-fos	18 to 24 (4 to 6 independent experiments with 4 replicates per experiment)
E: Static compressive loading	No change	No change in c-fos	8 (4 independent experiments with 2 replicates per experiment)
F: Cyclic compressive loading	No change	NA	8 (3 independent experiments with 2 to 3 replicates per experiment)