. Author manuscript; available in PMC: 2013 Feb 28.

Published in final edited form as: Eur J Pharmacol. 2011 Dec 14;677(1-3):180–187. doi: 10.1016/j.ejphar.2011.12.003

Table 2.

Effect of Treatment of High Fat/Streptozotocin Diabetic Rats with enalapril, candoxatril or ilepatril on Serum Thio Barbituric Acid Reactive Substances, Triglycerides, Free Fatty Acids, Cholesterol and ACE activity

Determination	Control (9)	Diabetic (9)	Diabetic + enalapril (8)	Diabetic + candoxatril (9)	Diabetic + ilepatril (8)
Thiobarbituric acid reactive substances (μg/ml)	0.82 ± 0.04	1.07 ± 0.07^a	0.97 ± 0.10	0.87 ± 0.07	0.83 ± 0.07^b
Triglycerides (mg/dl)	29 ± 3	107 ± 19^a	86 ± 17^a	65 ± 16	61 ± 15
Free fatty acids (mmol/l)	0.08 ± 0.02	0.41 ± 0.05^a	0.46 ± 0.10^a	0.35 ± 0.06^a	0.38 ± 0.04^a
Cholesterol (mg/ml)	1.8 ± 0.3	4.5 ± 0.8^a	2.2 ± 0.3	3.7 ± 0.5	1.8 ± 0.3^b
ACE (mU/ml/min)	54 ± 3	89 ± 4^a	2 ± 1^a,^b	78 ± 5	16 ± 2^a,^b

Data are presented as the mean ± S.E.M.

P < 0.05 compared to control;

p < 0.05 compared to diabetic. Parentheses indicate the number of experimental animals.