Figure 6.
Schematics depicting the potential cellular interaction and trafficking of WLS and MOR in rat striatal processes following opiate agonist treatment. A. Following saline treatment, WLS and MOR are associated with the plasma membrane while most WLS are localized within the cytoplasm. B. Following morphine treatment, the binding of morphine to MOR causes more WLS and MOR to translocate to the plasma membrane. C. Following DAMGO treatment, WLS and MOR remain within the cytoplasm where they are often associated with endosome-like vesicles.