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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Biomaterials. 2012 Jan 14;33(10):2952–2960. doi: 10.1016/j.biomaterials.2011.12.043

Figure 2. C60-serPF NPs localize to the nucleus liver cancer cells.

Figure 2

Panel A. Confocal microscopy image of Hep3B cells and Z-stack through the nucleus at the point depicted by the arrow. Intensity profiles through line 1, 2, and 3 are also represented, demonstrating colocalization with DAPI. Concentration of C60-serPF in the nucleus increases relative to cytoplasm as the cells are exposed to increasing concentrations of C60-serPF. Panel B. Nuclear uptake is confirmed by flow cytometry after extraction of nuclei demonstrating uptake in the majority of cells.