Effect of 2ME, taxol, and their co-administration on murine pulmonary permeability. (A, B) Mice subjected to intravenous administration of vehicle control, 10 mg/kg 2ME, 0.8 mg/kg taxol, and simultaneous administration of 2ME and taxol for 3h were analyzed for EBD-albumin (A) or water (B) accumulation in the lung tissue. C) Mice subjected to intravenous administration of vehicle control, 10 mg/kg 2ME, 0.4 mg/kg taxol, and simultaneous administration of 2ME and taxol for 3h were analyzed for EBD-albumin accumulation in the lung tissue. D) Mice subjected to intravenous administration of vehicle control, 10 mg/kg 2ME, 0.8 mg/kg taxol, and simultaneous administration of 2ME and taxol for 24h were analyzed for EBD-albumin accumulation in the lung tissue. Shown are mean±SEM, number of animals is indicated on the figure. *p<0.05 are considered significantly different.