Fig. 2.
Effects of gabapentin, pregabalin and riluzole on glutamate-induced glutamate release from astrocytes. Cells were treated with buffer or glutamate (10 μM) for 5 min in the presence of buffer alone, gabapentin (GBP, 1–100 μM), pregabalin (PGB, 10–100 μM), or riluzole (RIL, 0.1–1 μM). [3H]-glutamate release is presented as a percentage of total radioactivivity. Number in each column represents sample size. *P<0.01 vs. buffer alone. #P<0.01 vs. glutamate alone.