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. Author manuscript; available in PMC: 2013 Feb 28.
Published in final edited form as: Eur J Pharmacol. 2011 Dec 21;677(1-3):87–92. doi: 10.1016/j.ejphar.2011.12.015

Fig. 4.

Fig. 4

(A) Representative intracellular Ca2+ responses in astrocytes stimulated with glutamate (Glu) after perfused with gabapentin (GBP) or riluzole (RIL), presented as change in Fura-2 fluorescence ratio. (B) Effects of RIL and GBP on basal Fura-2 fluorescence ratio. Basal values were determined from the average ratio for 1 min before and after starting vehicle, RIL, or GBP perfusion. Number in each column represents sample size. (C) Effects of RIL (0.01–1 μM) and GBP (1–100 μM) on glutamate-induced intracellular Fura-2 response. Each box represents the 25th, 50th, and 75th percentiles of Fura-2 fluorescence ratio response. Number under each box represents sample size. *P<0.05 vs. control (10 μM glutamate alone).