Fig. 2.

Assessment of cell viability in human and mouse islet preparations. a The numbers of TUNEL-positive beta cells in representative human (black circles, n = 9) and mouse FVB (white squares, n = 4) islet preparations were determined. Analysis was based on counting approximately 3,000 and 1,200 beta cells per human and mouse islet sample, respectively; p = 0.0673. b The expression profile of apoptosis-related genes as labelled in human (n = 6) and (c) FVB mouse islets (n = 5) cultured in 5 (black bars) or 11 mmol/l (white bars) glucose. BCLX/Bclx, also known as BCL2L1/Bcl2l1