Table 4.
Patient characteristics of matched serous carcinoma samples
| Primary & postchemo n = 28 | Primary & recurrent n = 12 | |||||
|---|---|---|---|---|---|---|
| Age (mean, min-max, SD) | 55.1 | 31–74 | SD 9.3 | 49.8 | 31–68 | SD 12.1 |
| Age; grouped | n | % | n | % | ||
| < 58 | 13 | 46.4 | 8 | 66.7 | ||
| ≥ 58 | 15 | 53.6 | 4 | 33.3 | ||
| Missing | 0 | 0.0 | 0 | 0.0 | ||
| FIGO | n | % | n | % | ||
| Stage I | 0 | 0.0 | 1 | 8.3 | ||
| Stage II | 1 | 3.6 | 2 | 16.7 | ||
| Stage III | 22 | 78.6 | 8 | 66.7 | ||
| Stage IV | 5 | 17.9 | 1 | 8.3 | ||
| Grade | n | % | n | % | ||
| Grade I | 3 | 10.7 | 2 | 16.7 | ||
| Grade II | 4 | 14.3 | 3 | 25.0 | ||
| Grade III | 15 | 53.6 | 6 | 50.0 | ||
| Undifferentiated | 2 | 7.1 | 0 | 0.0 | ||
| Missing | 4 | 14.3 | 1 | 8.3 | ||
| Rest tumor after primary surgery | n | % | n | % | ||
| Yes | 28 | 100.0 | 4 | 33.3 | ||
| No | 0 | 0.0 | 7 | 58.3 | ||
| Missing | 0 | 0.0 | 1 | 8.3 | ||
| Size of rest tumor | n | % | n | % | ||
| < 2 cm | 1 | 3.6 | 7 | 58.3 | ||
| ≥ 2 cm | 25 | 89.3 | 2 | 16.7 | ||
| Missing | 2 | 7.1 | 3 | 25.0 | ||
| Chemotherapy | n | % | n | % | ||
| No chemo | 0 | 0.0 | 1 | 8.3 | ||
| Platinum based | 14 | 50.0 | 8 | 66.7 | ||
| Platinum/Taxane | 13 | 46.4 | 3 | 25.0 | ||
| Missing | 1 | 3.6 | 0 | 0.0 | ||
| Progression free survival (months) | ||||||
| (mean, min-max, SD) | 14.7 | 0–115 | SD 21.1 | 46.6 | 11–124 | SD 36.3 |
| FR-alpha expression (mean, median, SD) | ||||||
| Primary tumor | 1.29 | 1.0 | SD 0.897 | 1.17 | 1.0 | SD 1.03 |
| Interval debulking | 1.54 | 2.0 | SD 0.838 | |||
| Recurrent disease | 1.42 | 1.0 | SD 0.793 | |||
| p = 0.1 | p = 0.5 | |||||
| FR-alpha expression low/high (mean, median, SD) | ||||||
| Primary tumor | 0.36 | 0.0 | SD 0.488 | 0.4 | 0.0 | 0.515 |
| Interval debulking | 0.52 | 1.0 | SD 0.509 | |||
| Recurrent disease | 0.36 | 0.0 | 0.505 | |||
| p = 0.1 | p = 1.000 | |||||
Primary & Postchemo (middle column); cases containing tumor tissue from both primary surgery and interval debulking surgery (n = 28)
Primary & Recurrent (right column); cases containing tumor tissue from both primary surgery and from surgery for recurrent disease (n = 12)