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. 2012 Mar;13(1):16–27. doi: 10.2174/138920212799034776

Fig. (1).

Fig. (1)

Nucleotide skew plot for the Bacillus subtilis genome (NC_000964), with window size = 537179 and step size = 21078. Each data point is at the beginning of its sliding window. The replication origin is identified as the genomic site where the GC skew (SG) changes from negative to positive and the replication termination is the site where SG changes from positive to negative.