table 2. Comparison of the Previous Studies Regarding the Frequency of HFE Gene Mutations Among Patients With Different Types of Chronic Liver iseases in Different Geographic Locations.
| Target of Study | C282Y, % | H63D, % | |||
| Heterozygote | Homozygote | Heterozygote | Homozygote | ||
| USA[2] | Cryptogenic cirrhosis | 5.4 | 0.26 | 13.5 | 1.89 |
| USA[12] | HCV cirrhosis | 11.5 | 0 | 0 | 0 |
| Western Romania[13] | Various liver diseases | 4.8 | 19 | 9.5 | 0 |
| Germany [14] | Chronic hepatitis C | 6.6 | 0 | 34.9 | 3 |
| Brazil [15] | Chronic hepatitis C | 35 | 0 | 5 | 0 |
| Turkey [16] | Chronic liver disease | 1.7 | 0 | 28 | 2 |
| India [17] | Chronic liver disease | 0 | 0 | 14.8 | 0.4 |
| India [3] | Cryptogenic cirrhosis | 0 | 0 | 19.3 | 3.2 |
| Iran (Current study) | Cryptogenic cirrhosis | 0 | 0 | 22 | 0 |