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. 2012 Jan 24;3(1):6. doi: 10.1258/shorts.2011.011094

Table 1.

Description of the cases presented with dysrhythmia related to the use of H2O2

Case Age (years)/Gender Preoperative medications Type of surgery Requiring intervention Possible cause
1 60/M Yes – beta blockers Acute subdural hematoma removal – fronto temporo parietal craniotomy No TCR – chemical stimulation to trigeminal afferents
2 67/M No Chronic subdural hematoma removal – fronto temporo parietal cranitomy No TCR – chemical stimulation to trigeminal afferents
3 16/F No Pituitary adenoma – pterional craniotomy– No TCR
Anterior hypothalamus stimulation
Exothermic reaction of H2O2
4 15/M No Craniopharyngeoma – right frontal craniotomy No Mechanical stimulation of anterior hypothalamus
Exothermic reaction of H2O2
5 12/M No Posterior fossa surgery for cerebellar tumor – Midline suboccipital craniectomy No Mechanical stimulation of vital centres
Thermal irritation from the exothermic reaction from H2O2

TCR = trigemino-cardiac reflex, H2O2 = hydrogen peroxide