Table 1.
Clinical Characteristics of Study Subjects
| Clinical Characteristics | Gender | NG Controls n=1,124 595 M/529 F |
T2D Cases n=1,307 682 M/625 F |
p values | |
|---|---|---|---|---|---|
| Age (yr) | M | 51.3±15.2 | 55.6±11.4 | 6.1×10−10 | |
| F | 50.2±13.4 | 55.3±10.9 | 7.9×10−11 | ||
| Age at Diagnosis (yr) | M | -- | 46.9±11.2 | -- | |
| F | -- | 48.4±10.9 | -- | ||
| Duration of Diabetes (yr) | M | -- | 8.3±7.2 | -- | |
| F | -- | 7.0±6.3 | -- | ||
| Systolic Blood Pressure (mmHg) | M | 136.0±22.1 | 147.7±22.5 | 2.82×10−18 | |
| F | 135.2±24.3 | 148.1±24.4 | 1.50×10−17 | ||
| Diastolic Blood Pressure (mmHg) | M | 82.1±13.0 | 85.7±12.5 | 1.21×10−6 | |
| F | 81.0±12.5 | 84.9±11.7 | 1.47×10−7 | ||
| BMI (kg/m2) | M | 25.7±4.6 | 26.5±4.4 | 0.002 | |
| F | 26.9±5.8 | 28.2±5.45 | 0.001 | ||
| HDL-C (mg/dL) | M | 35.7±15.1 | 34.3±12.4 | 0.083 | |
| F | 41.0±15.3 | 38.3±12.9 | 0.007 | ||
| LDL-C (mg/dL) | M | 97.4±36.8 | 94.6±38.0 | 0.422 | |
| F | 105.1±36.4 | 106.3±35.9 | 0.077 | ||
| Fasting Blood Glucose (mg/dL) | M | 94.3±12.7 | 162.2±60.9 | 1.8×10−74 | |
| F | 94.3±12.9 | 163.3±64.0 | 1.5×10−59 | ||
| Total Cholesterol (mg/dL) | M | 165.1±55.9 | 167.1±47.4 | 0.705 | |
| F | 181.6±49.2 | 182.1±48.1 | 0.093 | ||
| Triglycerides (mg/dL) | M | 150.5±74.9 | 156.0±83.2 | 0.021 | |
| F | 145.2±68.5 | 160.1±84.5 | 0.015 | ||
| CETP Activity (pmoles/200 µL) | M | 195.6±32.0 | 189.5±33.6 | 0.186 | |
| F | 193.2±33.1 | 206.0±29.4 | 0.004 | ||
| CAD (%) | 11.4 | 16.9 | |||
| Alcohol Consumption (%) | |||||
| No Alcohol | M | 72 | 57 | -- | |
| F | 100 | 100 | -- | ||
| Moderate | M | 22 | 33 | -- | |
| F | 0 | 0 | -- | ||
| High | M | 6 | 10 | -- | |
| F | 0 | 0 | -- | ||
CAD-Coronary Artery Disease