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. 2012 Feb;23(2):294–304. doi: 10.1681/ASN.2011050490

Figure 5.

Figure 5.

Urinary MMP-7 correlates with its renal expression in adriamycin (ADR) nephropathy. (A) Urinary MMP-7 levels in mice. Mouse urinary MMP-7 protein was quantitatively determined by a specific ELISA and expressed as ng/mg creatinine. *P<0.05 versus sham controls and §P<0.05 versus vehicle (n=5). CTL, controls. (B) Representative Western blot analyses show renal MMP-7 protein expression in different groups as indicated. Numbers (1, 2, and 3) denote each individual animal in a given group. GAPDH, glyceraldehyde 3-phosphate dehydrogenase. (C) Representative RT-PCR results show renal MMP-7 mRNA expression 5 weeks after adriamycin injection. Numbers (1, 2, and 3) denote each individual animal in a given group. (D) Quantitative data on renal MMP-7 mRNA abundance in different groups as indicated. *P<0.05 and **P<0.01 versus sham controls and §P<0.05 versus vehicle (n=5).