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Aspiration injury. (A) In neonates, meconium aspiration is occasionally detected in diagnostic lung biopsies. Meconium is identified by loose aggregates of myxoid material, pigmented macrophages, and keratin flakes (*). (B) Aspiration of food particles in older children is associated with a granulomatous tissue response (*). Other features of aspiration in this case include chronic airway injury and lymphocytic bronchiolitis.
