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. Author manuscript; available in PMC: 2013 Jan 27.
Published in final edited form as: Immunity. 2011 Dec 28;36(1):68–78. doi: 10.1016/j.immuni.2011.12.007

Figure 5. Spare respiratory capacity in CD8+ T cells is dependent on mitochondrial FAO.

Figure 5

(A) Relative CPT1a mRNA expression in IL-2 TE and IL-15 TM cells (figure generated from data from 5 independent experiments); *P = 0.003. Oxygen consumption rates (OCR) in IL-15 TM cells (B), in IL-2 TE and IL-15 TM cells (C), and bona fide TE and TM cells isolated from LmOVA infected B6 mice (D), under basal conditions and in response to indicated drugs; P < 0.0001 (after FCCP in B left panel), < 0.01 (after etomoxir in B right panel), and < 0.0001 (for TM cells after etomoxir versus control, D). See also Figure S4.