PK PARAMETERS	UNITS		MOUSE BRAIN
			IV   1.0 mg eq./kg	PO   1.0 mg eq./kg	PO   10.0 mg eq./kg		SC   1.0 mg eq./kg	SC   10.0 mg eq./kg
AUC(0 - last)	nM hr/kg		36460	29660	311200		23600	351800
AUC(0- ¥ )	nM hr/kg		36590	29770	312300		25770	352800
AUCnorm	(nM hr/kg) /(kg/mg)		36590	29770	31230		25770	35280
Observed Cmax	nM		7698	4783	67680		5360	72520
Observed CmaxNorm	nM/ (mg/kg)		7698	4783	6768		5360	7252
Observed Tmax	hr		1.0	1.0	1.0		1.0	1.0
Half-life (t½)	hr		2.98	3.02	3.05		2.16	3.00
Half-life Regression Time Points	hr		2, 4, 8, 24	4, 8, 24	4, 8, 24		2, 4, 8	4, 8, 24
Ratio of Brain-to-Plasma AUC(0- ¥ )		24.98		24.03		17.09	17.98	16.07