Table 2.
Blacks | Whites | Overall | ||||
---|---|---|---|---|---|---|
Trait | β ± S.E. | P | β ± S.E. | P | β ± S.E. | P |
Type 2 diabetes# | 1.2 (0.9 – 1.5) | 0.2 | 1.4 (1.1 – 1.6) | 0.003 | 1.3 (1.1 – 1.5) | 0.001 |
Fasting glucose* | 0.02 ± 0.01 | 0.03 | 0.03 ± 0.007 | <0.001 | 0.03 ± 0.006 | <0.001 |
HbA1c* | 0.02 ± 0.007 | 0.02 | 0.02 ± 0.004 | <0.001 | 0.02 ± 0.004 | <0.001 |
Fasting Insulin* | 0.11 ± 0.03 | <0.001 | 0.13 ± 0.02 | <0.001 | 0.12 ± 0.02 | <0.001 |
HOMA-IR* | 0.13 ± 0.03 | <0.001 | 0.17 ± 0.02 | <0.001 | 0.13 ± 0.02 | <0.001 |
Adiponectin† | −0.11 ± 0.04 | 0.004 | −0.17 ± 0.03 | <0.001 | −0.16 ± 0.03 | <0.001 |
Obesity# | 1.3 (1.1 – 1.5) | 0.007 | 1.3 (1.1 – 1.5) | 0.007 | 1.3 (1.1 – 1.4) | <0.001 |
BMI | 0.60 ± 0.24 | 0.01 | 0.49 ± 0.17 | 0.003 | 0.60 ± 0.14 | <0.001 |
% total body fat | 0.85 ± 0.27 | 0.002 | 0.56 ± 0.21 | 0.009 | 0.74 ± 0.17 | <0.001 |
Leptin† | −0.07 ± 0.04 | 0.1 | 0.08 ± 0.04 | 0.02 | 0.02 ± 0.03 | 0.5 |
Visceral fat† | 0.21 ± 0.09 | 0.03 | 0.35 ± 0.08 | <0.001 | 0.29 ± 0.06 | <0.001 |
Subcutaneous fat† | 0.17 ± 0.09 | 0.06 | 0.008 ± 0.08 | 0.9 | 0.08 ± 0.06 | 0.2 |
For type 2 diabetes and obesity, values are odds ratios with 95% confidence interval.
Values were Log transformed.
Values were transformed into their squared-root equivalent.
Model: diabetes related trait = age + sex + race + site + BMI + education + CRP + physical activity + LDL + oxLDL + T2D Rx.
Adiposity related trait = age + sex + race + site + smoking + physical activity + LDL + oxLDL.